Project title:
Establishing thresholds for clinical importance for disease-specific EORTC questionnaire modules
Principal investigator:
PD Dr. Johannes M. Giesinger
Project coordinator:
Micha J. Pilz
Project summary
To improve interpretation of patient-reported outcome (PRO) data collected with the EORTC questionnaire modules the project develops thresholds for clinical importance for the following modules: QLQ-LC29 (lung), QLQ-PR25 (prostate), QLQ-BR45 (breast), QLQ-CR29 (colorectal), QLQ-NMIBC24, QLQ-BLM30 (bladder), QLQ-EN24 (endometrium), QLQ-H&N43 (head and neck), QLQ-CX24 (cervical cancer). These thresholds will facilitate interpretation of PRO scores collected in daily clinical practice and of trial results.
Collaborators
Juan I. Arraras (Medical Oncology Department, Hospital of Navarre, Pamplona, Spain)
Andrew Bottomley (Quality of Life Department, EORTC, Brussels, Belgium)
Anna Costantini (Dipartimento di Scienze Oncologiche, Sapienza Università di Roma, Rome, Italy)
Fabio Efficace (Health Outcomes Research Unit, Italian Group for Adult Hematologic Diseases (GIMEMA) Data Center, Rome, Italy)
Mogens Groenvold (The Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, and Department of Public Health, University of Copenhagen, Copenhagen, Denmark)
Bernhard Holzner (Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University of Innsbruck, Innsbruck, Austria)
Marieke van Leeuwen (Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands)
John Ramage (Department of Gastroenterology and Hepatology, Hampshire Hospitals NHS Foundation Trust, Aldermaston Road, Basingstoke, UK)
Heike Schmidt (University Hospital Halle (Saale), Department for Radiation Medicine, University Clinic and Outpatient Clinic for Radiotherapy, Halle (Saale))
Krzysztof A. Tomaszewski (Health Outcomes Research Unit, Department of Gerontology, Geriatrics, and Social Work, Ignatianum Academy, Krakow, Poland)
Teresa Young (Lynda Jackson Macmillan Centre, Mount Vernon Cancer Centre, Northwood, UK)
Katarzyna Pogoda (Department of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland)